Seth Mattson, John Peteet, & Shira Maguen
June 23, 2026
In clinical practice, trauma is often conceptualized through the lens of fear--manifesting as hyperarousal, avoidance, and intrusive reminders. For many patients, this framework is both accurate and clinically useful. However, not all trauma-related distress is primarily fear-based.
Some patients present with persistent guilt, anger, or shame that does not readily respond to standard cognitive or exposure-based approaches. These experiences may meet criteria for posttraumatic stress disorder (PTSD), yet the underlying source of distress can feel qualitatively different. Rather than fear alone, patients describe a disruption in their sense of what is right, just, or good--within themselves, others, or the broader world. This clinical presentation aligns with the construct of moral injury.
A Distinct Dimension of Trauma
Moral injury refers to distress that arises following events that transgress deeply held moral beliefs or expectations. Unlike PTSD, which is rooted in threat-based responding, moral injury reflects a disruption in value-based meaning systems.
Clinically, this may present as:
- Guilt related to actions taken (or not taken) under constraint
- Anger associated with witnessing acts of betrayal by individuals or institutions
- Shame tied to perceived changes in one's moral character
Importantly, these responses are not necessarily distortions. In many cases, they represent coherent moral appraisals of complex and constrained situations.
The Role of the DSM-5-TR Z-Code
The recent inclusion of the DSM-5-TR Z-code for "Moral, Religious, or Spiritual Problems" offers a practical framework for identifying these experiences in clinical care. This Z-code conceptualizes moral problems as disruptions in moral identity, including one's sense of:
- The goodness of self
- The goodness of others
- The moral integrity of institutions
- One's understanding of right and wrong
As a non-pathologizing designation, it allows clinicians to document and address morally laden distress alongside, but distinct form, primary psychiatric diagnoses.
Implications for Assessment of Moral Injury
The inclusion or moral problems as a z-code highlights the importance of accurate assessment to accurately capture those who have long-lasting and distressing symptoms due to a potentially morally injurious event versus those who have short-lived moral dilemmas that are more easily resolved. Key pointers for selecting measures include:
- The importance of measuring both a morally injurious event (exposure) as well as moral injury symptoms indexed to this event
- Attending to whether the measure has a clear cut score to determine clinically meaningful moral injury
- Choosing a measure that has a clear factor structure representing moral injury, rather than factors that overlap with other disorders
- Ensuring measures used are validated on diverse groups (e.g., demographics and occupational)
Implications for Treatment
The distinction between fear-based and morally based distress has meaningful implications for intervention. Trauma-focused therapies often emphasize cognitive restructuring, particularly when beliefs are inaccurate or exaggerated. However, in the context of moral injury, distress may stem from accurate moral judgements, rather than cognitive distortions. In these cases, premature reframing may risk invalidating the patient's experience.
A more effective approach may involve:
- Careful validation of moral pain
- Exploration of the patient's values and moral framework
- Differentiation between responsibility and constraint
- Facilitation of processes such as meaning-making, repair, and self-forgiveness
This approach does not replace evidence-based trauma therapies, but rather extends them to more fully address the moral and existential dimensions of trauma.
A Clinical Consideration
When patients present with persistent guilt, shame, or anger following trauma, it may be useful to ask:
Is this distress primarily driven by fear, or by a perceived violation of what is right?
Attending to this distinction can enhance diagnosis clarity and support more targeted, patient-centered care.
Discussion Questions
- How can clinicians distinguish between maladaptive cognitions and morally coherent distress in trauma presentations?
- What are the risks of applying standard PTSD interventions to morally grounded experiences without adaptation?
- How can clinicians best assess for moral injury in routine trauma assessment?
- How might moral identity be incorporated into routine trauma assessment?
About the Authors
Seth Mattson, M.D., is a psychiatry resident with research interests in moral injury, trauma, and the integration of clinical psychiatry with moral and existential frameworks.
John Peteet, M.D., is a Professor of Clinical Psychiatry at Harvard Medical School, Brigham and Women's Hospital, and Dana-Farber Cancer Institute, Boston.
Shira Maguen, Ph.D., is a Professor of Psychiatry and Behavioral Sciences at University of California, San Francisco and Staff Psychologist at the San Francisco VA Healthcare System.
Reference Article
Mattson, S. A., Peteet, J. R., & Maguen, S. (2026). Differentiating moral injury from posttraumatic stress disorder: Implications of the DSM-5-TR moral problems Z-code. Journal of Traumatic Stress, 1–9. https://doi.org/10.1002/jts.70089
References
Griffin, B. J., Price, L. R., Jenkins, Z., Childs, A., Tong, L., Raciborski, R. A., Weber, M. C., Pyne, J. M., Maguen, S., Norman, S. B., & Vogt, D. (2025). A systematic review and meta-analysis of moral injury outcome measures. Current Treatment Options in Psychiatry, 12(1), Article 7. https://doi.org/10.1007/s40501-024-00342-9
Litz, B. T., & Walker, H. E. (2025). Moral Injury: An Overview of Conceptual, Definitional, Assessment, and Treatment Issues. Annual review of clinical psychology, 21(1), 251–277. https://doi.org/10.1146/annurev-clinpsy-081423-022604
Mattson, S., VanderWeele, T. J., Lu, F., Carey, L. B., Cowden, R. G., Fung, E. N., Koenig, H. G., Peteet, J., & Wortham, J. (2025). Moral, Religious, or Spiritual Problem: An Expanded Z Code Diagnostic Category in the DSM-5-TR. The Journal of nervous and mental disease, 213(11), 297–304. https://doi.org/10.1097/NMD.0000000000001856
Mattson, S. A., Iv, F. K., Tanev, K. S., Matta, S. E., Levy-Carrick, N. C., Peteet, J. R., & Stern, T. A. (2026). Moral Injury: Appreciating Its Impact and Managing Its Sequelae. The primary care companion for CNS disorders, 28(1), 25f04100. https://doi.org/10.4088/PCC.25f04100
Peteet J. R. (2024). The Moral Dimension of Mental Health Treatment. Journal of psychiatric practice, 30(2), 157–161. https://doi.org/10.1097/PRA.0000000000000775
